ChemPubSoc Europe is an organization of 16 European chemical societies, founded in the late 1990s as a consequence of the amalgamation of many chemical journals owned by national chemical societies into a number of high-quality European journals.
ChemPubSoc Europe's journals, all published with Wiley-VCH, are: Chemistry—A European Journal, European Journal of Organic Chemistry, European Journal of Inorganic Chemistry, ChemBioChem, ChemPhysChem, ChemMedChem, ChemSusChem, ChemCatChem, ChemPlusChem, ChemElectroChem, ChemistryOpen, and ChemViews, the ChemPubSoc Europe e-zine. They replaced 16 traditional national chemistry journals.
The participating societies share a commitment to scientific excellence, to publishing ethics, and to the highest standards in publication, which are the basis for the success of the ChemPubSoc Europe journals.
ChemPubSoc Europe and its Asian sister organization, the Asian Chemical Editorial Society (ACES), mutually support each other in the publication of their journals Chemistry—A European Journal, Chemistry—An Asian Journal, and ChemSusChem.
© Wiley-VCH 2009–2013
The latest impact factors for the ChemPubSoc Europe journals are as follows (2013):
|Chemistry A—European Journal||5.696|
|European Journal of Organic / Inorganic Chemistry||3.145 / 2.965|
|ChemPhysChem / ChemElectroChem||3.360 / n/a|
|ChemBioChem / ChemMedChem||3.060 / 3.046|
|ChemSusChem / ChemCatChem||7.117 / 5.044|
|ChemPlusChem / ChemistryOpen||3.242 / 2.938|
The synthesis of optically active spiroimines, one of the pharmacophores of the marine neurotoxin gymnodimine A, is described. The approach relies on a three-step sequence that includes a palladium-catalyzed asymmetric decarboxylative alkylation, an isomerization and a [3+2]-cycloaddition reaction of an azidoalkene to build the imine.
Matt Rambla, Leslie Duroure, Laurent Chabaud, Catherine Guillou
Eur. J. Org. Chem., October 24, 2014, DOI: 10.1002/ejoc.201403161. Read article.
The attempted structure elucidation and total synthesis of a naturally occurring antidiabetic drug led to the synthesis of two higher monosaccharides by using an olefination, cross-coupling, and oxidation reaction sequence. This synthetic strategy paves the way to a new class of substances that is not yet well investigated.
Melchior Menzel, Thomas Ziegler
Eur. J. Org. Chem., October 24, 2014, DOI: 10.1002/ejoc.201403140. Read article.
Click chemistry was used to build a series of nonpeptide Arg-Gly-Asp (RGD) peptidomimetics. Integrin binding assays revealed heterocyclic guanidine bioisosteres that showed binding activity and also indicated a minor role played by the aromatics on the azide fragment. Modelling showed that the triazole and 2-aminopyridine rings interact with Tyr178 of αvβ3 integrin.
Pierangelo Fabbrizzi, Gloria Menchi, Silvia Raspanti, Antonio Guarna, Andrea Trabocchi
Eur. J. Org. Chem., October 24, 2014, DOI: 10.1002/ejoc.201403129. Read article.
A synthesis of isotopically labelled oligoprenyl diphosphates was developed. This method allows for the introduction of labelling into every position or combination of positions. [14-2H]Geranylgeranyl diphosphate was used in an incubation experiment with tuberculosinyl diphosphate synthase from Mycobacterium tuberculosis, giving insight into the stereochemical course of the terpene cyclase reaction.
Christian A. Citron, Patrick Rabe, Lena Barra, Chiaki Nakano, Tsutomu Hoshino, Jeroen S. Dickschat
Eur. J. Org. Chem., October 24, 2014, DOI: 10.1002/ejoc.201403002. Read article.
CO2 catalysis: A CO2-influenced, improved dehydrogenation protocol is described using trans-Rh(PMe3)2(CO)Cl as a catalyst. Alkanes and liquid organic hydrogen carriers are used as substrates under benign homogeneous reaction conditions. High catalyst turnover numbers as well as high yields are obtained because of the prevention of catalyst deactivation.
Abhishek Dutta Chowdhury, Jennifer Julis, Kathleen Grabow, Bernd Hannebauer, Ursula Bentrup, Martin Adam, Robert Franke, Ralf Jackstell, Matthias Beller
ChemSusChem, October 24, 2014, DOI: 10.1002/cssc.201402850. Read article.
PEEK and ye shall find: To reconcile the tradeoff between conductivity and dimensional stability in anion exchange membranes, a novel Gemini quaternary ammonium poly (ether ether ketone) (GQ-PEEK) membrane was successfully synthesized. The GQ-PEEK membranes exhibited enhanced ionic conductivity and fuel cell performance while undergoing only moderate swelling.
Jiangju Si, Shanfu Lu, Xin Xu, Sikan Peng, Ruijie Xiu, Yan Xiang
ChemSusChem, October 24, 2014, DOI: 10.1002/cssc.201402664. Read article.
Ca-lling on oxides: Powders of calcium manganese oxide (Ca–birnessite) are screen printed onto conductive substrates that are used as anodes in water electrolysis. Screening of various transition-metal oxides for electrochemical water oxidation under “artificial leaf conditions” is possible and confirms the suitability of Ca–Mn-oxides for this task.
Seung Y. Lee, Diego González-Flores, Jonas Ohms, Tim Trost, Holger Dau, Ivelina Zaharieva, Philipp Kurz
ChemSusChem, October 24, 2014, DOI: 10.1002/cssc.201402533. Read article.
Talkin' about our generation: Copper-based metal oxide (CuO, CuO/Co3O4) nanoparticles have been synthesized from coordination-driven self-assembling aggregates and calcination treatment. They exhibited exceptional catalytic activity and stability for the selective oxidation of styrene and its derivatives to generate the corresponding aldehydes (see figure; TBHP=tert-butyl hydroperoxide).
Danhua Ge, Jiaqing Wang, Hongbo Geng, Shuanglong Lu, Dongtao Wang, Xinming Li, Xianli Zhao, Xueqin Cao, Hongwei Gu
ChemPlusChem, October 24, 2014, DOI: 10.1002/cplu.201402319. Read article.
Studying ArSe: An unpaired electron of αNpSeSeαNp.− is localized in the Se-Se σ* orbital with an elongated Se-Se bond at 77 K. As the temperature increases, αNpSeSeαNp.− changes to Intermediate.− with an absorption at longer wavelength owing to the conformational change, in which an unpaired electron is delocalized in the interaction between the π* and σ* orbital (see scheme).
Sachiko Tojo, Mamoru Fujitsuka, Akihiko Ouchi, Tetsuro Majima
ChemPlusChem, October 24, 2014, DOI: 10.1002/cplu.201402300. Read article.
“With the manuscript having been prepared during the soccer world cup, we found in this theme an apposite analogy to our ”sugar championship“ aiming at labeling cell-surface glycans.” Read more about the story behind the cover in the Cover Profile and about the research itself on page ██ ff. (DOI: 10.1002/chem.201404716).
Anne-Katrin Späte, Verena F. Schart, Sophie Schöllkopf, Andrea Niederwieser, Valentin Wittmann
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201405618. Read article.
“The structure of the cluster is unusually unorganized compared to most other clusters.” Read more about the story behind the cover in the Cover Profile and about the research itself on page ██ ff. (DOI: 10.1002/chem.201404763).
Miguel A. Huertos, Israel Cano, Nuno A. G. Bandeira, Jordi Benet-Buchholz, Carles Bo, Piet W. N. M. van Leeuwen
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201405452. Read article.
Power with a control switch: Enhanced spatiotemporal selectivity in photonic sensitization of dissolved molecular oxygen is an important target for improving the potential and practice of photodynamic therapy. Considering the high glutathione (GSH) concentrations in cancer cells, a series of BODIPY-based “caged” sensitizers have been designed and synthesized. The sensitizers can generate cytotoxic singlet oxygen only after glutathione-mediated cleavage of the electron-sink module.
Ilke Simsek Turan, Fatma Pir Cakmak, Deniz Cansen Yildirim, Rengul Cetin-Atalay, Engin U. Akkaya
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201405450. Read article.
Zeolite analogues: A germanate zeolite PKU-14 with a 3D 12-ring channel system was synthesized and structurally characterized by the combination of high-resolution PXRD, RED, NMR, and IR spectroscopy. Ordered Ge4O4 vacancies inside the [46.612] cage were found in PKU-14, in which a unique (H2O)2 dimer was located at the vacancies and played a structure-directing role (see scheme).
Jie Liang, Jie Su, Yingxia Wang, Yanping Chen, Xiaodong Zou, Fuhui Liao, Jianhua Lin, Junliang Sun
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201405449. Read article.
Silver nanowires: Single-crystal conformations of various α, γ4-hybrid peptide 12-helices incorporated with γ4-Val, γ4-Leu and γ4-Phe residues and their supramolecular assemblies are studied. Hybrid peptide 12-helices composed of alternating α- and γPhe residues displayed unique elongated nanotubes. Further, we explored the utility of these nanotubes for the fabrication of silver nanowires from silver ions (see figure).
Sandip V. Jadhav, Rajkumar Misra, Hosahudya N. Gopi
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201404961. Read article.
Decorating macrocycles! A family of shape-persistent alleno–acetylenic macrocycles (SPAAMs), peripherally decorated with structurally diverse pendant groups, has been synthesized in enantiomerically pure form. Their electronic circular dichroism spectra feature a strong chiroptical response, which is not reduced by large achiral peripheral substituents. The first optically active, water-soluble oligo(ethylene glycol) (OEG)-appended SPAAMs were prepared and further characterized by cryo-TEM, revealing the formation of aggregates with fibrous fine structures that correspond to tubular, macrocyclic stacks.
Manolis D. Tzirakis, Mariza N. Alberti, Haim Weissman, Boris Rybtchinski, François Diederich
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201404941. Read article.
Direct cyanation: A straightforward synthesis of 1,2-dicyanoalkanes by the reaction of nitroalkenes with trimethylsilyl cyanide in the presence of tetrabutylammonium fluoride (TBAF) is reported (see scheme). The method has wide substrate scope and tolerates a wide variety of functional groups. Mechanistic studies suggest that a small amount of water present in the reaction media plays a key role in the reaction.
Kensuke Kiyokawa, Takaya Nagata, Junpei Hayakawa, Satoshi Minakata
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201404780. Read article.
Smooth operation: The key feature in the enantioselective total synthesis of the lignan, (+)-linoxepin, is a Pd-catalyzed domino reaction consisting of a carbopalladation and a Mizoroki–Heck reaction using DavePhos as a bulky electron-rich ligand and an AgI salt as additive to suppress aromatization. The stereogenic center was introduced by an asymmetric regioselective hydroboration to give the natural product.
Lutz F. Tietze, Jérôme Clerc, Simon Biller, Svenia-C. Duefert, Matthias Bischoff
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201404679. Read article.
Most accurately: A new wet chemical functionalization sequence for carbon allotropes applying λ3-iodanes is presented (see figure). By coupling thermogravimetric analysis with gas-chromatographic separation and mass-spectrometric characterization an exact determination of the degree of functionalization becomes feasible.
Ferdinand Hof, Ricarda A. Schäfer, Cornelius Weiss, Frank Hauke, Andreas Hirsch
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201404662. Read article.
Adjustable complexes: The electronic properties of a nonaromatic oxatriphyrin(3.1.1) change drastically by a trigonal-to-tetrahedral rehybridization at the C3 linker (see figure). The triheterocyclic brace of a free base presets an intensive emission, strongly depending on the solvent viscosity and robustly affecting the excited-state lifetimes. A similar relationship has been observed for boron(III) complexes of phlorin-like oxatriphyrin(3.1.1)
Miłosz Pawlicki, Aneta Kędzia, Dominik Bykowski, Lechosław Latos-Grażyński
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201404570. Read article.
Safe haven for sulfur: Core–shell hierarchical porous carbon (HPC) spheres were synthesized by a facile hydrothermal method and used as host to incorporate sulfur. The resulting material turns out to be highly uniform and exhibit enhanced specific capacity, superior rate capability, and excellent cycling stability when evaluated as a cathode material for lithium–sulfur batteries.
Fei-Fei Zhang, Gang Huang, Xu-Xu Wang, Yu-Ling Qin, Xin-Chuan Du, Dong-Ming Yin, Fei Liang, Li-Min Wang
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201404439. Read article.
POM–drug hybrids: A systematic investigation of aliphatic organoimido derivatives of a polyoxometalate (POM) based on the drug amantadine elucidated the spectral and crystal-structural similarities and differences between monosubstituted, cis-disubstituted, and trans-disubstituted derivatives (see figure) to provide guidance for related work on imido-functionalized Lindqvist-type POMs. Furthermore, covalently grafting a biologically active molecule to a POM enhanced its applications in clinical cancer treatment.
Shan She , Shengtai Bian, Jian Hao , Jiangwei Zhang, Jin Zhang , Yongge Wei
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201404317. Read article.
A less taxing route to taxol: The Pd-catalyzed intramolecular alkenylation of a methyl ketone affords a key cyclized intermediate for the synthesis of (−)-taxol in excellent yield (97 %) (see scheme; Bn=benzyl; TES=triethylsilyl). Rearrangement of an epoxy benzyl ether through a 1,5-hydride shift, generating the C3 stereogenic center and subsequently forming the C1–C2 benzylidene, was discovered during the preparation of a substrate for the Pd-catalyzed reaction.
Sho Hirai, Masayuki Utsugi, Mitsuhiro Iwamoto, Masahisa Nakada
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201404295. Read article.
Bimodal imaging probe: A new bispidine–BODIPY building block has been developed, enabling simultaneous bimodal imaging by positron emission tomography (PET; radioactive 64Cu) and optical imaging (fluorescence dye). Further functionalization with targeting vectors can be achieved using the C1 and C2 positions of the bispidine scaffold.
Holger Stephan, Martin Walther, Silke Fähnemann, Paola Ceroni, Jennifer K. Molloy, Giacomo Bergamini, Fabian Heisig, Christa E. Müller, Werner Kraus, Peter Comba
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201404086. Read article.
Highly decorated: Nanocomposites were prepared by in situ growth of ZnO nanocrystals on the surface of reduced graphene oxide (RGO) that was homogeneously decorated with poly(N-vinylpyrrolidone) (PVP; see figure). ZnO@RGO-PVP has higher conductivity, fewer defects and traps, and higher LUMO energy level than bare ZnO. Using ZnO@RGO-PVP as cathode buffer layer improved the power conversion efficiency of an inverted polymer solar cell to 7.5 % with long-term stability.
Ting Hu, Lie Chen , Kai Yuan, Yiwang Chen
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201404025. Read article.
A hybrid α1-Dawson polyanion bearing a lateral side chain with a 4-aminopyridine end group catalyzes the addition of indenyl allyl silanes to cinnamoyl fluorides. The chiral polyanionic framework influences the catalytic activity, the selectivity, and the stereoselectivity of the reaction (see figure).
Christian Brazel, Nathalie Dupré, Max Malacria, Bernold Hasenknopf, Emmanuel Lacôte, Serge Thorimbert
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201403989. Read article.
Benzene- and thiophene-substituted coumarin-3-aldehyde derivatives were developed using rational design for the fluorescent sensing of primary-amine neurotransmitters (e.g., glutamate, norepinephrine, and dopamine). The degree of photoinduced electron transfer (PET) from the aryl moiety to the fluorophore and consequently the fluorescence output of the analyte-bound sensor can be predetermined solely using DFT energy-level calculations.
Kenneth S. Hettie, Timothy E. Glass
Chem. Eur. J., October 24, 2014, DOI: 10.1002/chem.201403128. Read article.
A(n ionic) liquid diet: A mutation that improves the stability of formate dehydrogenases in ionic liquids and causes a 5.8-fold enhancement of the kcat value was identified. The site is located at the monomer–monomer interface and influences the local pKa values, including an increase in the pKa of residue E163 from 4.8 to 5.5.
Julie L. L. Carter, Mourad Bekhouche, Alexandre Noiriel, Loïc J. Blum, Bastien Doumèche
ChemBioChem, October 24, 2014, DOI: 10.1002/cbic.201402501. Read article.
It's just not natural! The production of new isopropylstilbene derivatives was achieved by mutasynthesis with a Photorhabdus ASD (anthraquinone and stilbene deficient) mutant, blocked in anthraquinone and cinnamic acid biosynthesis. Chemical synthesis of selected compounds allowed for their biological evaluation, which led to compounds with better activity than the natural products.
Max Kronenwerth, Alexander O. Brachmann, Marcel Kaiser, Helge B. Bode
ChemBioChem, October 24, 2014, DOI: 10.1002/cbic.201402447. Read article.