Mission Statement
ChemPubSoc Europe is an organization of 14 European chemical societies, founded in the late 1990s as a consequence of the amalgamation of many chemical journals owned by national chemical societies into a number of high-quality European journals.
ChemPubSoc Europe co-owns and supports these journals including Chemistry—A European Journal, European Journal of Organic Chemistry, European Journal of Inorganic Chemistry, ChemBioChem, ChemPhysChem, ChemMedChem, ChemSusChem, and ChemCatChem which are published by Wiley-VCH.
The participating societies share a commitment to scientific excellence, to publishing ethics, and to the highest standards in publication, which are the basis for the success of the ChemPubSoc Europe journals.
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News
On May 21, 2010, ChemPhysChem and ChemBioChem celebrate their 10th anniversary with a one-day symposium in Paris. Ten speakers, including four Nobel laureates, will discuss the frontiers of chemistry.
Research of the Day
Current Rectification in Temperature-Responsive Single Nanopores
A fully abiotic smart single-nanopore device that rectifies ionic current in response to the temperature is reported. The temperature-responsive nanopore ionic rectifier can be switched between a rectifying state below 34 °C and a non-rectifying state above 38 °C actuated by the phase transition of the poly(N-isopropylacrylamide) [PNIPAM] brushes (see picture).
[Article]
Wei Guo, Hongwei Xia, Fan Xia, Xu Hou, Liuxuan Cao, Lin Wang, Jianming Xue, Guangzhao Zhang, Yanlin Song, Daoben Zhu, Yugang Wang, Lei Jiang
ChemPhysChem, February 5, 2010, DOI: 10.1002/cphc.200900989. Read article.
Taking Quinazoline as a General Support-Nog to Design Potent and Selective Kinase Inhibitors: Application to FMS-like Tyrosine Kinase 3
Molecular joinery: Herein we propose a concept for the design of selective kinase inhibitors. This de novo design method involves restricted fragment growth by using quinazoline as a general molecular support-nog. Application of this concept to the design of FMS-like tyrosine kinase 3 (FLT3) inhibitors led to a potent (IC50=7 nM) and selective FLT3 inhibitor.
[Communication]
Wei-Wei Li, Jin-Juan Chen, Ren-Lin Zheng, Wen-Qin Zhang, Zhi-Xing Cao, Ling-Ling Yang, Xiao-Yu Qing, Liang-Xue Zhou, Li Yang, Luo-Ding Yu, Li-Juan Chen, Yu-Quan Wei, Sheng-Yong Yang
ChemMedChem, February 5, 2010, DOI: 10.1002/cmdc.200900537. Read article.
Studying the Origin of the Antiferromagnetic to Spin-Canting Transition in the β-p-NCC6F4CNSSN. Molecular Magnet
Spin transitions: The transition from antiferromagnetism to spin canting in the β-p-NCC6F4CNSSN. molecular magnet is investigated by using a first-principles theoretical procedure. Spin canting below 36 K is due to the presence of two ferromagnetic sublattices that are antiferromagnetically coupled (see figure). The evolution of the ferromagnetic JAB contributions explains the change in the slope of the residual χ in the low-temperature region.
[Full Paper]
Mercè Deumal, Jeremy M. Rawson, Andrés E. Goeta, Judith A. K. Howard, Royston C. B. Copley, Michael A. Robb, Juan J. Novoa
Chem. Eur. J., February 5, 2010, DOI: 10.1002/chem.200903221. Read article.
Antiferromagnetism or Delocalized Spin in a Cu3S2 Core?
Is there a bond or isn't there? In a further effort to bring light to the debate on the existance of an S-S bond in Tolman's cluster compound (shown here), this correspondence is a reply to the preceeding communication.
[Correspondence]
Santiago Alvarez, Eliseo Ruiz
Chem. Eur. J., February 5, 2010, DOI: 10.1002/chem.200903153. Read article.
The First General, Efficient and Highly Enantioselective Reduction of Quinoxalines and Quinoxalinones
Simple yet efficient: A series of diverse substituted tetrahydroquinoxalines and dihydroquinoxalinones have been synthesized for the first time in a highly enantioselective fashion (see scheme). Using this metal-free hydrogenation it is possible to isolate these products, which are of high pharmaceutical interest, in good yields and with excellent enantioselectivities in a minimal number of reaction steps.
[Communication]
Magnus Rueping, Francisco Tato, Fenja. R. Schoepke
Chem. Eur. J., February 5, 2010, DOI: 10.1002/chem.200902907. Read article.
Biaryl Phosphite–Oxazoline Ligands from the Chiral Pool: Highly Efficient Modular Ligands for the Asymmetric Pd-Catalyzed Heck Reaction
Highly active: A library of phosphite–oxazoline ligands is applied to asymmetric Pd-catalyzed Heck reactions of several substrates and triflates under thermal and microwave conditions. By carefully selecting the ligand components, high activities, regioselectivities, and enantioselectivities (>99 % ee) are achieved (see scheme).
[Full Paper]
Javier Mazuela, Oscar Pàmies, Montserrat Diéguez
Chem. Eur. J., February 5, 2010, DOI: 10.1002/chem.200902777. Read article.
UC Pd: A New Form of Pd/C for Sonogashira Couplings
Larger and better? “UC Pd”, a new form of Pd/C; it has a nice “ring” to it… (the charcoal!). More importantly, easily fashioned and recyclable UC Pd heterogeneously catalyzes Sonogashira couplings without copper, and in cheap and environmentally benign 95 % EtOH at 50 °C. Most commercial sources of Pd/C for these cross-couplings have been tested and found not to work nearly as well, nor can they be readily recycled.
[Full Paper]
Christophe Duplais, Arnold J. Forman, Benjamin A. Baker, Bruce H. Lipshutz
Chem. Eur. J., February 5, 2010, DOI: 10.1002/chem.200902471. Read article.
A Definitive Answer to a Bonding Quandary? The Role of One-Electron Resonance Structures in the Bonding of a {Cu3S2}3+ Core
Does the complex contain an S-S bond? This question has been recently debated by Alvarez, who claims that there is no S-S bond, and Mealli and Hoffmann, who claim there is an S-S bond. Here, these two opposing viewpoints are reconciled by an in-between alternative for the electronic structure that is supported by DFT calculations and the available experimental data. The compound (see picture) is described as the first that has been recognized to contain the unusual S23− ion, having a three-electron sulfur–sulfur σ bond and an S-S bond order of 0.5.
[Communication]
John F. Berry
Chem. Eur. J., February 5, 2010, DOI: 10.1002/chem.200902324. Read article.
A Light-Controlled Molecular Brake with Complete ON–OFF Rotation
Molecular brake: A cyclic azobenzenophane-based molecular brake with complete ON–OFF rotation controlled by light is presented (see picture). Its mode of operation has been delineated with the aid of 1H NMR, chiral HPLC, and circular dichroism (CD) spectroscopy. Photoinduced E–Z isomerization of the azobenzene moiety results in free rotation of a naphthalene rotor unit being OFF in the trans isomer (small cyclophane cavity; brake on) but ON in the cis isomer (large cyclophane cavity; brake off).
[Full Paper]
Meethale C. Basheer, Yoshimi Oka, Manoj Mathews, Nobuyuki Tamaoki
Chem. Eur. J., February 5, 2010, DOI: 10.1002/chem.200902123. Read article.
One-Dimensional Ferromagnetically Coupled Bimetallic Chains Constructed with trans-[Ru(acac)2(CN)2]−: Syntheses, Structures, Magnetic Properties, and Density Functional Theoretical Study
The chain gang! Four cyano-bridged 1D bimetallic polymers were prepared with the paramagnetic building block trans-[Ru(acac)2(CN)2]− (Hacac=acetylacetone); an example is shown here. Two compounds are 1D, zigzagged NiRu chains that exhibit ferromagnetic coupling between NiII and RuIII ions, whereas another has a 1D linear chain structure that exhibits metamagnetic behavior. The fourth one is a novel single-chain magnet, that consists of Mn2Ru trimers linked together by noncovalent interactions.
[Full Paper]
Jun-Fang Guo, Xiu-Teng Wang, Bing-Wu Wang, Guan-Cheng Xu, Song Gao, Lap Szeto, Wing-Tak Wong, Wai-Yeung Wong, Tai-Chu Lau
Chem. Eur. J., February 5, 2010, DOI: 10.1002/chem.200902047. Read article.
A 93Nb Solid-State NMR and Density Functional Theory Study of Four- and Six-Coordinate Niobate Systems
Measurement and calculation: A comprehensive variable B0 93Nb broadline solid-state NMR study of a large suite of niobate-based materials is reported. Correlations involving the elucidated 93Nb NMR parameters suggest that the NbV site is directly influenced by both the immediate oxo environment and the more distant heavy elements comprising the material structure (see figure).
[Full Paper]
John V. Hanna, Kevin J. Pike, Thibault Charpentier, Thomas F. Kemp, Mark E. Smith, Bryan E. G. Lucier, Robert W. Schurko, Lindsay S. Cahill
Chem. Eur. J., February 5, 2010, DOI: 10.1002/chem.200901581. Read article.
Cloning and Characterization of the Ravidomycin and Chrysomycin Biosynthetic Gene Clusters
Deciphering the biosyntheses of gilvocarcin-type anticancer drugs: Ravidomycins and chrysomycins are important members of the gilvocarcin-type antitumor drugs. Cloning, sequencing, and functional analysis of the gene clusters of ravidomycin from Streptomyces ravidus and chrysomycin from S. albaduncus gave insights into the biosynthetic pathways of these drugs and could expand the toolbox for combinatorial biosynthetic engineering of optimized future analogues.
[Full Paper]
Madan K. Kharel, S. Eric Nybo , Micah D. Shepherd , Jürgen Rohr
ChemBioChem, February 5, 2010, DOI: 10.1002/cbic.200900673. Read article.